10 months after the release of Super Meat Boy, Edmund McMillen has put out his next game, The Binding of Isaac, a horror-themed top-down shooter that takes its name from the Biblical story where Abraham is asked by God to sacrifice his son. The game features short, randomly-generated levels with 100 items, over 50 monsters, and 20 bosses. The soundtrack is by Danny Baranowsky.
Note: Isaac is not a Team Meat release. The programmer for this one is Florian Himsl, who previously collaborated with Edmund on Cunt and Twin Hobo Rocket. Team Meat has purportedly started work on their next project.