Version 1.0 of George Moromisato’s Transcendence was released recently. Transcendence is a real-time space exploration game that draws inspiration from roguelikes and has randomly-generated star systems and items, among other things (there is no permadeath, however – you get a single save slot that can be reloaded after death). It plays similarly to the Escape Velocity series.
The game’s first public release (v0.7) came out nearly 7 years ago, and the game has been in development since 1995!
(Thanks, BellosTheMighty, for the heads-up.)
TIGdb: Entry for Transcendence